I didn’t want my developer friends feeling left out, so I thought I would share some items that are new or different in Visual Studio 2015 and SharePoint Server 2016, from a developer’s standpoint.
You’ve heard the expression “location, location, location” before, and this most definitely applies to SharePoint Server 2016. Developers need to know where to store their customizations so they are available for use from within SharePoint Server 2016.
Similar to previous versions of SharePoint, there is a dedicated folder that contains the important-for-devs subfolders, including the GAC, Resources, TEMPLATE and CONFIG. The root system directory for SharePoint Server 2016 is the 16 folder, or to be more specific, the Program Files->Common Files->Microsoft Shared->Web Server Extensions->16. If I recall correctly, 16.n is also for SharePoint Online, so be careful when working from within Visual Studio.
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Source: COMPUTER WORLD